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Reactive aldehyde fragrance

TRANS, TRANS-2,4-DECADIENAL

CAS 25152-84-5
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

trans,trans-2,4-Decadienal is a reactive unsaturated aldehyde used as a flavor and fragrance note. PubChem flags it as a skin and eye irritant with respiratory irritation potential, limiting its safe-use range on skin.

Skin benefits

  • Natural-occurring aldehyde contributing fatty, fried-fat or aged-fragrance notes used in flavors and perfumery
  • Found in many cooked foods, lending an authentic flavor character

Known concerns

  • PubChem GHS Warning with H312 harmful in skin contact, H315 skin irritation and H319 serious eye irritation
  • H335 may cause respiratory irritation in some classifications
  • Reactive alpha,beta-unsaturated aldehyde that can form Michael adducts with skin proteins, raising sensitization potential
  • Limited dermal safety dossier for direct leave-on cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.