Skip to content

TRI (GAMMA-GLUTAMYL CYSTEINYL) GLYCINE

87

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A glutathione-like tripeptide that supports skin's antioxidant defense and detoxification pathways, generally regarded as safe with no EU restrictions.

Tri(gamma-glutamyl cysteinyl) glycine, essentially a glutathione tripeptide analog, is a synthetic peptide supporting skin's endogenous antioxidant defense system. Glutathione is a naturally occurring skin antioxidant that declines with age and UV exposure. Not restricted in EU Annexes. Peptide-based ingredients of this type are generally well-tolerated with low irritation and sensitization potential, though stability in formulation (oxidation) can be a challenge.

Skin benefits

  • Supports skin's natural antioxidant defense
  • Detoxification pathway support (phase II conjugation)
  • Skin brightening via tyrosinase inhibition
  • Anti-aging and pollution defense benefits

Known concerns

  • Formulation stability (oxidation sensitivity)
  • Limited penetration if not properly formulated

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Same plant / compound family

75
TRI (GAMMA-GLUTAMYL) GLUTAMINE
Skin Conditioning

Check your shelf

Find TRI (GAMMA-GLUTAMYL CYSTEINYL) GLYCINE in your products.

Scan any cosmetic product with LuxSense to see if it contains TRI (GAMMA-GLUTAMYL CYSTEINYL) GLYCINE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.