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Triamterene (INN) and its salts

CAS 396-01-0
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Triamterene (inn) And Its Salts is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Triamterene (INN) is a pharmaceutical diuretic used to treat hypertension and edema by acting on the distal renal tubule. Its hazard profile (H302 acute toxicity, H315 skin irritation, H319 eye irritation, H335 respiratory irritation) is consistent with a systemic drug having significant off-target effects including hyperkalemia risk. Triamterene has no cosmetic function whatsoever—it is not a fragrance, preservative, UV filter, or any recognized cosmetic ingredient class. Its presence in cosmetic products would constitute adulteration under EU cosmetic regulation, triggering market withdrawal and regulatory action.

Known concerns

  • Pharmaceutical drug with no cosmetic function — likely adulteration if present
  • GHS H302: harmful if swallowed
  • GHS H315/H319/H335: skin, eye, and respiratory irritation
  • Systemic toxicity risk including hyperkalemia; requires medical supervision

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.