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TRIHYDROXYBENZAMIDOHEXYL TRIPHENYLPHOSPHONIUM BROMIDE

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A phosphorylated aromatic compound designed for topical use, typically developed for its antioxidant and anti-aging properties. The triphenylphosphonium moiety helps drive the active into skin layers.

Trihydroxybenzamidohexyl Triphenylphosphonium Bromide is a brominated salt bearing a triphenylphosphonium cation conjugated to a trihydroxybenzamidohexyl amide. The triphenylphosphonium group is lipophilic and tends to accumulate in mitochondria, making this class of compounds of interest for topical anti-aging applications. The bromine counterion (bromide) contributes minimal toxicity. Used in advanced cosmetic formulations targeting oxidative stress in skin.

Skin benefits

  • Mitochondrial-targeted antioxidant activity
  • Potential anti-aging effects
  • May help reduce oxidative damage in skin

Known concerns

  • May cause mild skin irritation in sensitive individuals
  • Limited long-term safety data available

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.