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UV photoinitiator (nail)

TRIMETHYLBENZOYL DITOLYLPHOSPHINE OXIDE

CAS 270586-78-2
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A phosphine oxide photoinitiator related to TPO, used in UV-cured gel nail products. The TPO family is banned in the EU from 2025 as a reproductive toxicant, making this ingredient high concern.

Skin benefits

  • Effective UV photoinitiator for gel nail polish curing
  • Provides fast, reliable cure under LED lamps
  • Yields hard, glossy nail coatings

Known concerns

  • Belongs to the TPO photoinitiator family banned in the EU from September 2025
  • Parent TPO classified as Category 1B reproductive toxicant under CLP
  • Potential skin sensitization risk from uncured photoinitiator residue
  • Regulatory status in flux globally; future restrictions likely

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.