Chelating Agent
TRIMETHYLDECENEDIONE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A small diketone chelator used for metal binding and stability in cosmetic formulas. Novel; public safety data is limited so default-cautious.
Trimethyldecenedione (CAS 13851-06-4) is a medium-chain alkenyl dione structurally capable of chelating metal ions through its diketone motif. It is positioned in cosmetics as a chelating agent and antioxidant support molecule. The alpha,beta-unsaturated diketone chemistry can be reactive toward biological nucleophiles (Michael acceptor), raising theoretical sensitization concern. Cosmetic use is typically at low concentrations (0.01-0.5%). No CIR or SCCS review is published; default-cautious scoring applies. The previously recorded 85 score is revised downward because the class reactivity and lack of public data do not support green tier.
Function
Skin benefits
- Small chelating/antioxidant molecule — can bind metal ions
- Emerging cosmetic active with formulation stability benefits
- Low use concentrations
Known concerns
- Alpha-beta-unsaturated diketone motif can be reactive (Michael acceptor)
- No CIR or SCCS review
- Limited public safety data
- Odor/irritation at high use levels
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related chelating agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.