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TRIMETHYLOLPROPANE

CAS 77-99-6
82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Trimethylolpropane is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Trimethylolpropane (TMP, 2-ethyl-2-(hydroxymethyl)propane-1,3-diol) is a triol that functions as a humectant, emollient, and viscosity-controlling agent in cosmetic formulations. It has low acute oral toxicity (LD50 > 10,000 mg/kg in rats), is not a skin sensitizer, and is not listed in EU CosIng Annexes as restricted or prohibited. It is used in skin care, hair care, and color cosmetic formulations at typical concentrations of 1-10%. Cosmetic ingredient safety is supported by its chemical inertness and lack of systemic toxicity at use concentrations.

Skin benefits

  • Humectant - attracts and retains skin moisture
  • Emollient properties improve skin softness
  • Used as a carrier or co-solvent in cosmetic formulations
  • Contributes to product texture and sensory profile

Known concerns

  • Very low acute toxicity; standard handling precautions sufficient
  • May contain residual traces of formaldehyde as an impurity from manufacturing

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.