Prohibited Substance
Trioxsalen [USAN]
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
4,5',8-Trimethylpsoralen, used in PUVA photochemotherapy. EU-banned in cosmetics under Annex II — psoralens combined with UVA are IARC Group 1 carcinogens.
Skin benefits
- Not a cosmetic ingredient
Known concerns
- EU Annex II prohibited
- Psoralen + UVA carcinogenic class
- Severe photosensitizer
- Prescription drug
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related prohibited substances
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.