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Skin Conditioning

TRIPEPTIDE-117 CITRULLINE

67

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A combined INCI of designer tripeptide-117 with the amino acid citrulline, used for skin conditioning. Citrulline is well-tolerated; the peptide has limited independent data.

This combination INCI represents a supplier blend of designer Tripeptide-117 with the free amino acid citrulline (a non-protein amino acid involved in nitric oxide pathways). Citrulline is widely used in cosmetics and oral supplements with a strong safety record. The tripeptide component is proprietary, used at trace ppm levels, with no independent CIR or SCCS review. The blend is intended for skin-conditioning effects. Conservative tier: yellow with low evidence — citrulline pulls slightly upward, the unknown peptide pulls back.

Function

SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Citrulline-supported skin conditioning
  • Trace-level peptide signaling
  • Low irritation profile

Known concerns

  • Limited independent safety data on the tripeptide
  • No CIR/SCCS review for combination
  • Supplier-driven efficacy claims

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related skin conditionings

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.