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Skin Conditioning

TRIPEPTIDE-149 CYCLO (MESITYL OCTAPEPTIDE-71) TETRAPEPTIDE-158

Updated
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An engineered tripeptide-cyclic-mesityl-octapeptide-tetrapeptide construct used at trace amounts for targeted skin signaling. No public safety data; class is sparsely reviewed.

Skin benefits

  • Highly engineered cyclic-peptide construct for targeted signaling
  • Used at very low percentages
  • Mesityl-cyclic form designed for protease resistance

Known concerns

  • Mesityl (trimethylphenyl) group is non-natural; toxicology not publicly reviewed
  • No public safety data for this construct
  • Cyclic-peptide class has limited cosmetic safety literature

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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ACETYL MONOFLUOROHEPTAPEPTIDE-1
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ACETYL TRIPEPTIDE-108 N-ACETYL LYSYL GLUTAMINE
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ACETYLSALICYLIC ACID
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ACINETOBACTER/SOYBEAN SEED EXTRACT FERMENT
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.