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Skin Conditioning

TRIPEPTIDE-51

68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Tripeptide-51 — a proprietary signalling peptide. Plausible at low use levels; evidence base is mostly supplier-driven.

Tripeptide-51 is a synthetic three-amino-acid peptide used in cosmetics for skin-conditioning and anti-ageing claims. Listed in EU CosIng; no dedicated SCCS opinion. Use levels are typically in the parts-per-million range. Public toxicological data is limited; manufacturer dossiers provide in-vitro and small in-vivo tolerance data. Evidence level low. Standard profile for a modern synthetic peptide active.

Function

ANTIMICROBIAL, ANTIOXIDANT, ASTRINGENT, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

Skin benefits

  • Synthetic signalling peptide
  • Low-use-level exposure
  • Short-term tolerance

Known concerns

  • Proprietary evidence base
  • No SCCS dossier
  • Thin peer-reviewed data

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.