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tris(2-Chloroethyl) phosphate

CAS 115-96-8
22

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Tris(2-chloroethyl) Phosphate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Tris(2-chloroethyl) phosphate (CAS 115-96-8), also known as TCEP, is a chlorinated organophosphate flame retardant. Extensive GHS hazard statements include H302 (harmful if swallowed), H320 (causes eye irritation), H351 (suspected of causing cancer), H360F (may damage fertility), H361 (suspected of damaging the unborn child), H370 (causes damage to organs), H372 (causes damage to organs through prolonged or repeated exposure), H373 (may cause damage to organs), H316 (causes mild skin irritation), H336 (may cause drowsiness or dizziness), H340 (may cause genetic defects), H401 (toxic to aquatic life), H411 (toxic to aquatic life with long-lasting effects). This substance has multiple classifications that make it unsuitable for cosmetic use. Not listed for cosmetic applications in EU CosIng Annexes. The compound has been restricted in the EU for use in consumer products due to its toxicity profile.

Known concerns

  • Suspected carcinogen (H351)
  • Reproductive toxicity (H360F, H361)
  • Mutagenic concern (H340)
  • Organ toxicity (H370, H372)
  • Aquatic toxicity (H411)
  • Neurotoxicity potential (H336)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.