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TRIS-METHYLGLUCAMMONIUM CHLORIN E6

CAS 1354645-32-1
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Tris-methylglucammonium Chlorin e6 is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Tris-Methylglucammonium Chlorin E6 is a chlorin (porphyrin derivative) used in cosmetic photodynamic applications. The chlorin structure absorbs light in the red/near-infrared region, generating reactive oxygen species upon illumination. It is not listed in EU Annex II (banned), but photosensitizing compounds require careful evaluation. Limited long-term safety data exist, and use is typically restricted to low concentrations in specifically designed formulations.

Skin benefits

  • Photodynamic activity for targeted skin treatments
  • Potential for photorejuvenation applications
  • Antimicrobial activity under light activation

Known concerns

  • Photosensitization potential - generates reactive oxygen species
  • Limited long-term safety data in cosmetic formulations
  • Potential for phototoxic reactions
  • Requires protection against light during storage and use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.