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Conditioning Agent

VALPROIC ACID

CAS 99-66-1
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A pharmaceutical active with serious reproductive and organ-toxicity baggage. That is miles away from what you want in a comfortably low-risk cosmetic ingredient.

Valproic Acid is a branched-chain fatty acid best known as a drug substance rather than as a routine cosmetic ingredient. The batch data flags major GHS concerns including reproductive toxicity, possible harm to breast-fed children, skin and eye irritation, and target-organ toxicity with repeated exposure. Even if cosmetic exposure would usually be lower than oral drug exposure, the underlying toxicology profile is too serious for a good score.

Function

SKIN CONDITIONING

Skin benefits

  • Skin conditioning

Known concerns

  • Reproductive toxicity concern
  • May cause harm to breast-fed children
  • Target-organ toxicity concern
  • Skin and eye irritation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related conditioning agents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.