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Skin Conditioning

VALPROOYL OLIGOPEPTIDE-33

35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A peptide conjugated with valproic acid (the anticonvulsant). Valproic acid is an EU-classified reproductive toxicant strictly contraindicated in pregnancy, so this conjugate carries serious safety baggage in cosmetics.

Function

SKIN CONDITIONING

Skin benefits

  • Marketed as a hair-growth signal peptide
  • Lipophilic conjugate aids follicle penetration
  • Used at low active concentration

Known concerns

  • Valproic acid is an EU-classified Reproductive Toxicant Cat 1A
  • Pregnancy-incompatible — risk of foetal valproate syndrome
  • Topical valproic acid derivatives lack SCCS approval for cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.