Skin Conditioning
VALPROOYL OLIGOPEPTIDE-33
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A peptide conjugated with valproic acid (the anticonvulsant). Valproic acid is an EU-classified reproductive toxicant strictly contraindicated in pregnancy, so this conjugate carries serious safety baggage in cosmetics.
Function
Skin benefits
- Marketed as a hair-growth signal peptide
- Lipophilic conjugate aids follicle penetration
- Used at low active concentration
Known concerns
- Valproic acid is an EU-classified Reproductive Toxicant Cat 1A
- Pregnancy-incompatible — risk of foetal valproate syndrome
- Topical valproic acid derivatives lack SCCS approval for cosmetic use
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.