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Adaptogenic botanical

WITHANIA SOMNIFERA LEAF POWDER

CAS 90147-43-6
76

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Ashwagandha leaf powder is rich in withanolides with antioxidant and anti-inflammatory effects. Clinical data support its use in topical anti-aging formulas, though leaf concentrations are pharmacologically active.

Skin benefits

  • Adaptogen with antioxidant and anti-inflammatory withanolides
  • Clinical study (Cureus 2023) showed improvement of photoaged skin parameters at 8 percent topical use
  • Soothes irritated and sensitive skin
  • Long history in Ayurvedic skin care

Known concerns

  • Leaf contains higher withanolide content than root, with stronger pharmacological activity
  • Possible cytotoxic effect at high concentrations (melanoma cell studies)
  • Limited large-scale cosmetic safety opinion
  • Possible interactions with thyroid or immune conditions on systemic exposure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Same plant / compound family

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.