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Prohibited drug (alpha-adrenergic agonist)

Xylometazoline

CAS 526-36-3
8

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Xylometazoline is a prescription nasal decongestant, not a cosmetic ingredient. It is prohibited in EU cosmetic products and any cosmetic use is an illegal and potentially harmful adulteration.

Skin benefits

  • No legitimate cosmetic benefit
  • Only used as a prescription nasal decongestant

Known concerns

  • Active pharmaceutical ingredient, not for skin care
  • Prohibited from EU cosmetic products under Annex II
  • Vasoconstrictor with risk of rebound effects and systemic absorption
  • Documented toxicity in children at small doses
  • Cosmetic presence indicates illegal adulteration

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related prohibited drug (alpha-adrenergic agonist)s

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.