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Skin Conditioning

ZANTHOXYLUM AMERICANUM/CLAVA-HERCULES BARK EXTRACT

58

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Prickly-ash bark extract — sanshool alkaloids deliver a tingling/numbing sensation. Effective in lip and toning products but the pharmacologically active alkaloids and phototoxicity flags warrant caution.

Function

SKIN CONDITIONING

Skin benefits

  • Lignan and alkaloid actives offer skin tingling
  • Mild antimicrobial action
  • Traditional toning use

Known concerns

  • Sanshool-class alkaloids are paraesthesia agents (numbing/tingling)
  • Sensitisation potential on broken skin
  • Phototoxicity flagged for related Zanthoxylum species

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.