ZANTHOXYLUM PIPERITUM OIL
Other
Moderate
CAS Number: 97404-53-0
About ZANTHOXYLUM PIPERITUM OIL
An essential oil from Sichuan pepper (Zanthoxylum piperitum) with skin sensitization potential due to its amide and alkaloid content, requiring careful evaluation before use in cosmetic formulations.
Detailed Analysis
Zanthoxylum Piperitum Oil is obtained from the fruit and fruit pericarp of Zanthoxylum piperitum (Rutaceae), also known as Japanese prickly ash or Sichuan pepper. The oil contains alkylamides (particularly sanshool compounds), limonene, and various terpene derivatives that contribute to its characteristic citrusy-biting aroma. The sanshool amides are known to cause a unique tingling sensation and have raised concerns regarding potential neurotoxic effects at high concentrations. EU Annex III does not currently list Zanthoxylum specifically, but the alkylamide content warrants caution and the ingredient requires standard fragrance allergen declaration considerations.
What It Does
Skin Benefits
- ✓ Distinctive citrus-peppery fragrance
- ✓ Provides unique sensory tingling effect
Known Concerns
- ⚠ Sanshool amides - potential skin and mucous membrane irritation
- ⚠ Sensitization potential from amide constituents
- ⚠ May require D-limonene and linalool fragrance allergen declaration
Safety Score
Moderate
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.