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ZERUMBONE

CAS 471-05-6
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Zerumbone is a cosmetic ingredient. Exercise caution due to limited available safety data.

Zerumbone is a sesquiterpene ketone found in ginger essential oil (Zingiber zerumbet). It carries H317 (may cause allergic skin reaction) and H400 (very toxic to aquatic life) hazard statements under CLP Regulation 1272/2008. While not explicitly listed in EU Cosmetics Regulation 1223/2009 annexes, the H317 classification means it should be handled as a fragrance allergen. Environmental concerns (H400) require attention to formulation type and disposal. Use concentrations should remain below sensitization thresholds.

Skin benefits

  • Anti-inflammatory and antioxidant properties
  • Potential anti-aging and skin-soothing benefits

Known concerns

  • Skin sensitization H317: potential allergic contact dermatitis
  • Aquatic toxicity H400: environmental concern
  • Should be declared as potential fragrance allergen on EU labels
  • Essential oil-derived; composition may vary

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.