(3-Chloro-2-hydroxypropyl) trimethylammonium chloride
Other
Caution
CAS Number: 3327-22-8
About (3-Chloro-2-hydroxypropyl) trimethylammonium chloride
This quaternary ammonium compound is primarily used in industrial water treatment and textile processing, carrying concerns about potential carcinogenicity and environmental aquatic toxicity.
Detailed Analysis
(3-Chloro-2-hydroxypropyl) trimethylammonium chloride (CHPTAC) is a quaternary ammonium salt with a chlorinated hydroxypropyl group. It is classified as H351 (suspected of causing cancer) under CLP regulation. The compound is primarily used as an intermediate in the production of cationic starch for paper and textile industries and cationic polymers for water treatment. It is not listed in EU cosmetics regulation Annexes, effectively prohibiting cosmetic use. Its quaternary ammonium structure raises concerns about persistence and potential endocrine-disrupting properties, while the epoxide-forming potential in certain conditions adds to its hazard profile.
Known Concerns
- ⚠ Suspected carcinogen (H351)
- ⚠ No EU cosmetic approval
- ⚠ Potential epoxide formation
- ⚠ Environmental aquatic toxicity
- ⚠ Persistence concerns
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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