5-Chloro-2-(2,4-dichlorophenoxy)phenol

Other

38

Caution

CAS Number: 3380-34-5

About 5-Chloro-2-(2,4-dichlorophenoxy)phenol

5-chloro-2-(2,4-dichlorophenoxy)phenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Detailed Analysis

5-Chloro-2-(2,4-dichlorophenoxy)phenol, also known as triclocarban or a close analog, is a chlorinated aromatic ether-phenol compound. Under EU Regulation (EC) No 1223/2009 Annex V/26, it is permitted as a preservative at a maximum concentration of 0.3% in ready-to-use formulations. The compound carries significant hazard classifications including H315 (skin irritation), H319 (serious eye irritation), H331 (toxic by inhalation), H335 (may cause respiratory irritation), and H400/H410 (aquatic toxicity). The SCCS has raised concerns about endocrine-disrupting potential and environmental persistence, similar to triclosan. In the EU, it is restricted to rinse-off products only and requires specific warning statements on packaging.

Skin Benefits

  • ✓ Antimicrobial preservative function

Known Concerns

  • ⚠ EU Annex V restricted preservative (0.3% max in rinse-off products)
  • ⚠ Skin and eye irritant (H315, H319)
  • ⚠ Toxic by inhalation (H331)
  • ⚠ Suspected endocrine disruption
  • ⚠ Environmental persistence and aquatic toxicity

Safety Score

38

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.