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5-Chloro-2-(2,4-dichlorophenoxy)phenol

CAS 3380-34-5
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

5-chloro-2-(2,4-dichlorophenoxy)phenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

5-Chloro-2-(2,4-dichlorophenoxy)phenol, also known as triclocarban or a close analog, is a chlorinated aromatic ether-phenol compound. Under EU Regulation (EC) No 1223/2009 Annex V/26, it is permitted as a preservative at a maximum concentration of 0.3% in ready-to-use formulations. The compound carries significant hazard classifications including H315 (skin irritation), H319 (serious eye irritation), H331 (toxic by inhalation), H335 (may cause respiratory irritation), and H400/H410 (aquatic toxicity). The SCCS has raised concerns about endocrine-disrupting potential and environmental persistence, similar to triclosan. In the EU, it is restricted to rinse-off products only and requires specific warning statements on packaging.

Skin benefits

  • Antimicrobial preservative function

Known concerns

  • EU Annex V restricted preservative (0.3% max in rinse-off products)
  • Skin and eye irritant (H315, H319)
  • Toxic by inhalation (H331)
  • Suspected endocrine disruption
  • Environmental persistence and aquatic toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.