Skip to content

Other

4-NITRO-O-PHENYLENEDIAMINE DIHYDROCHLORIDE

CAS 6219-77-8
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Nitro-O-Phenylenediamine Dihydrochloride is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This nitro-substituted phenylenediamine is used as a primary intermediate in oxidative hair dye formulations. The EU CosIng database classifies it under Annex III restrictions, permitting use only after special certification. Its nitro group and diamine structure contribute to its skin-sensitizing potential, and it may cross-react with other azo dye intermediates.

Known concerns

  • Skin sensitizer (H317 - may cause allergic skin reaction)
  • Harmful if swallowed (H302)
  • Potential carcinogen concerns with nitroaromatic compounds
  • Cross-reactivity with other hair dye intermediates

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

38
1-[(4-Methyl-2-nitrophenyl)azo]-2-naphthol
Other
 38
2,2'-[(4-Amino-3-nitrophenyl)imino]bisethanol hydrochloride and its salts
Other
 38
2,3-Dichloro-2-methylbutane
Other
 38
2-HEXYLOXY-P-PHENYLENEDIAMINE HCL
Other
 38
2-T-BUTYLCYCLOHEXYL ACETATE
Other
 38
2-[(3-Amino-4-methoxyphenyl)amino]ethanol and its sulphate
Other
 38
3-Amino-7- (dimethylamino)-2- methoxyphenoxazin- 5-ium chloride
Other
 38
3-NITRO-P-HYDROXYETHYLAMINOPHENOL
Other

Check your shelf

Find 4-NITRO-O-PHENYLENEDIAMINE DIHYDROCHLORIDE in your products.

Scan any cosmetic product with LuxSense to see if it contains 4-NITRO-O-PHENYLENEDIAMINE DIHYDROCHLORIDE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.