Other
4-NITRO-O-PHENYLENEDIAMINE HCL
Safety score · 0–100
Caution
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Nitro-O-Phenylenediamine Hcl is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.
4-Nitro-o-phenylenediamine HCl is the salt form of 4-nitro-o-phenylenediamine, similarly listed in EU Annex III of Regulation 1223/2009 for restricted use in oxidative hair dye products. The HCl salt form increases water solubility and may facilitate dermal absorption, potentially increasing exposure to the nitroaromatic compound. Hazard statements include H302 (harmful if swallowed), H312 (harmful in contact with skin), and H341 (suspected of causing genetic defects).
Skin benefits
- Hair dye intermediate
Known concerns
- EU Annex III restricted for hair dye use
- H341 mutagenicity concern
- H302/H312 acute toxicity
- Skin sensitizer
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.