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2,2'-METHYLENEBIS 4-AMINOPHENOL

CAS 63969-46-0
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

2,2'-methylenebis 4-aminophenol is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

2,2'-Methylenebis 4-Aminophenol is a hair dye intermediate with structural alerts for respiratory sensitisation, skin sensitisation, and environmental hazard (H400/H410 aquatic toxicity). While not explicitly listed in EU Annex II or III from the available CoSing data, its hazard profile — including serious eye damage, specific target organ toxicity, and aquatic toxicity — makes it a compound of concern requiring careful safety evaluation before cosmetic use.

Known concerns

  • Respiratory sensitisation potential
  • Serious eye damage (H318)
  • Skin sensitisation
  • Aquatic toxicity H400/H410
  • Specific target organ toxicity (STOT)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.