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2-AMINO-4-NITROPHENOL SULFATE

CAS 89418-01-9
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A sulfate salt of a nitro-phenol restricted under EU Annex II due to its toxicological profile and potential for metabolic activation.

This nitro-phenol sulfate is listed in EU Cosmetics Regulation Annex II/383, the list of substances forbidden in cosmetic products. The nitro group metabolizes to reactive hydroxylamine species capable of binding to cellular macromolecules. Its use in any cosmetic formulation is prohibited in the European Union.

Known concerns

  • EU Annex II banned substance (II/383)
  • Metabolic activation to reactive intermediates
  • Prohibited in cosmetic products in the EU
  • Potential for systemic toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.