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Skin Conditioning

ABELMOSCHUS MANIHOT CALLUS EXTRACELLULAR VESICLES

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Nano-vesicles isolated from cultured Abelmoschus manihot (sunset hibiscus) plant cells. Marketed for hydration and barrier support, but lightly studied.

Abelmoschus manihot callus extracellular vesicles are lipid-bilayer nanoparticles harvested from plant cell cultures of Abelmoschus manihot, a hibiscus species traditionally rich in mucilage and flavonoids. They are used in cosmetics as a vegan, plant-derived alternative to mammalian exosomes, with claims around hydration, barrier support, and antioxidant signalling. The class is novel and lacks any SCCS or CIR opinion; safety data rests on supplier dossiers. The parent plant has a long history of food and topical use without significant safety concerns, but cosmetic-specific evidence for the vesicle preparation is thin.

Function

SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING, SKIN CONDITIONING - HUMECTANT, SKIN CONDITIONING - MISCELLANEOUS

Skin benefits

  • Plant-derived hydrating signals
  • Sustainable plant-callus source
  • Generally low irritation

Known concerns

  • Novel ingredient class with no SCCS or CIR opinion
  • Efficacy claims supplier-driven
  • Limited published toxicology

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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Same plant / compound family

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ABELMOSCHUS MANIHOT FLOWER EXTRACT
Humectant
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ABELMOSCHUS MANIHOT FLOWER WATER
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ABELMOSCHUS MANIHOT LEAF EXTRACT
Humectant
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ABELMOSCHUS MANIHOT ROOT EXTRACT
Humectant

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.