Skin Conditioning
(SH-OLIGOPEPTIDE-78 S-FRUIT FLY OLIGOPEPTIDE-1) PEPTIDES
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A recombinant peptide blend including a fruit-fly-derived oligopeptide. Novel and under-studied in public cosmetic safety literature.
This material is a peptide blend that combines sh-Oligopeptide-78 (a synthetic/recombinant human-sequence peptide) with an oligopeptide originally derived from Drosophila (fruit fly) sequence, produced recombinantly. It is marketed for skin-signalling and repair claims. EU CosIng lists synthetic oligopeptides in general terms; there is no Annex II/III restriction but no formal CIR or SCCS review specific to this blend. As with most recombinant peptides, systemic exposure is minimal due to poor skin penetration of peptides. The unusual fruit-fly origin and very limited public safety dossier warrant caution.
Skin benefits
- Recombinant peptide complex with targeted signalling claims
- Small peptides typically well tolerated
- Low allergen risk at use levels
Known concerns
- Very novel ingredient, limited independent safety data
- Drosophila-derived peptide is unusual in cosmetics
- Proprietary data, low evidence level
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related skin conditionings
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.