Skip to content

Other

ACETAMIDOETHOXYBUTYL TRIMONIUM CHLORIDE

CAS 221375-78-6
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A conditioning quaternary ammonium compound with an acetamido-ethoxy side chain, designed to improve the feel of hair and skin formulations.

This ingredient functions as an antistatic and hair-conditioning agent. The acetamido moiety is relatively well tolerated, and the PubChem safety score of 72 reflects moderate confidence in its safety profile. It is not listed in EU Annex II or III, suggesting it is not subject to specific bans or restrictions. As with all quaternary ammonium compounds, it may cause mild irritation at high concentrations.

Skin benefits

  • Antistatic — reduces static charge in hair
  • Conditions and softens hair fiber

Known concerns

  • Mild skin and eye irritation possible at high concentrations
  • Not individually assessed in EU Annexes — general cosmetic safety provisions apply

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

72
1-ACETOXY-2-METHYLNAPHTHALENE
Other
 72
2,4-DIMETHYL-3-CYCLOHEXENE-1-METHYLACETATE
Other
 72
2-T-BUTYLCYCLOHEXANOL
Other
 72
2-T-BUTYLCYCLOHEXYLOXYBUTANOL
Other
 72
4-METHYLBENZALDEHYDE
Other
 72
ACETAMIDOETHYL PG-TRIMONIUM CHLORIDE
Other
 72
ACETYLCEDRENE
Other
 72
ADIPIC ACID/1,4-BUTANEDIOL/TEREPHTHALATE COPOLYMER
Other

Check your shelf

Find ACETAMIDOETHOXYBUTYL TRIMONIUM CHLORIDE in your products.

Scan any cosmetic product with LuxSense to see if it contains ACETAMIDOETHOXYBUTYL TRIMONIUM CHLORIDE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.