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ACETAMIDOETHYL PG-TRIMONIUM CHLORIDE

CAS 167614-36-0
72

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A quaternary ammonium conditioning agent with an acetamido group that enhances substantivity to hair and skin, providing durable conditioning effects.

A functionalized quaternary ammonium salt incorporating an acetamidoethyl moiety linked via a propyleneglycol bridge to the quaternary nitrogen. The amide group increases polarity and substantivity to keratin, providing durable conditioning even in rinse-off applications. The existing PubChem score of 72 reflects its status as a moderately studied cosmetic ingredient with some potential for skin sensitization at high concentrations. No specific EU Annex restrictions identified.

Skin benefits

  • Long-lasting conditioning deposition on hair
  • Softens and reduces static
  • Improves wet combing performance

Known concerns

  • Potential for skin sensitization at elevated concentrations
  • Some irritation reported in concentrated form
  • Eye contact may cause redness

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.