Solvent
Acetonitrile
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Acetonitrile — a polar aprotic solvent used in HPLC and synthesis. Banned in EU cosmetics under Annex II; metabolizes to cyanide and is acutely toxic.
Skin benefits
- No cosmetic use (laboratory solvent)
Known concerns
- EU Annex II banned in cosmetics
- Metabolizes to cyanide on systemic exposure
- Acutely toxic if inhaled or ingested
- Eye and skin irritant
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related solvents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.