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Fragrance

ANETHOLE

CAS 104-46-1 Updated
60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Anethole — the sweet licorice/anise fragrance molecule from star anise and fennel. IFRA-restricted with documented sensitisation potential and some endocrine signals in animal studies; use within limits is broadly tolerated.

Skin benefits

  • Sweet licorice/anise fragrance note
  • Mild antimicrobial activity
  • Natural occurrence in star anise and fennel

Known concerns

  • IFRA-restricted fragrance allergen
  • Documented sensitiser at higher concentrations
  • Endocrine-effect signals in animal studies — relevance to topical use is low
  • Photo-toxicity concerns in some formulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

PC

PubChem

U.S. NIH compound data, GHS hazard codes and toxicity literature.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.