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Skin Conditioning

ASIMINA TRILOBA LEAF EXTRACT

Updated
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

American pawpaw leaf extract used as a niche botanical antioxidant. The Annonaceae family carries acetogenins linked to neurotoxicity in oral exposure, so leaf extracts earn caution.

Function

HUMECTANTSKIN CONDITIONING

Skin benefits

  • Antioxidant phenolics
  • Skin conditioning
  • North American native botanical

Known concerns

  • Pawpaw contains acetogenins (annonacin) – mitochondrial toxins
  • Topical evidence sparse
  • Long-term safety unestablished

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.