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BENZALKONIUM BROMIDE

CAS 91080-29-4
40

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A quaternary ammonium biocide with broad-spectrum antimicrobial activity, permitted in cosmetics but subject to specific concentration limits in the EU.

Benzalkonium chloride/bromide is a mixture of alkylbenzyldimethylammonium salts widely used as a preservative and antimicrobial agent. EU Annex V (preservatives) permits benzalkonium chloride with specific concentration limits; the bromide analogue has similar regulatory treatment. III/65 and V/54 references in CosIng confirm specific restrictions. H314 (skin burns) and H318 (serious eye damage) require careful formulation to avoid irritation.

Skin benefits

  • Broad-spectrum preservative extending product shelf life
  • Antimicrobial efficacy against bacteria and fungi

Known concerns

  • H314/H318: severe skin and eye irritation at use concentrations
  • H317: contact sensitisation reported
  • H400: acute aquatic toxicity
  • CMR classification for certain chain lengths under review

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.