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Preservative

BENZETHONIUM CHLORIDE

CAS 121-54-0 Updated
35

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A strong cationic antiseptic. Effective at killing germs but the GHS profile is severe — corrosive to skin and eyes — and the EU restricts it tightly. Not a friendly ingredient for daily skincare.

Skin benefits

  • Antimicrobial preservation

Known concerns

  • EU restricted (Annex V max 0.1% rinse-off, banned in oral)
  • GHS H314 skin corrosion
  • H318 serious eye damage
  • Quat cytotoxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.