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Skin Conditioning

BIS-RETINOYL GEROTINE BIS-HYDROXYSUCCINIMIDE

CAS 666854-47-3 Updated
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A novel double-retinoid linker designed to slowly release retinoids on skin. Same class concerns as all retinoids: irritation, sun sensitivity, and pregnancy caution.

Function

ANTIOXIDANTANTI-SEBUM

Skin benefits

  • Retinoid-conjugated active for anti-aging
  • Slow-release retinoid for milder profile
  • Marketed as next-gen retinoid

Known concerns

  • Retinoids can cause irritation, peeling, and redness
  • Photo-instability and pregnancy caution
  • No independent SCCS/CIR review of this specific molecule

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.