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BUTYL 3,4-DIHYDROXYBENZOATE

60

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Butyl 3,4-dihydroxybenzoate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Butyl 3,4-dihydroxybenzoate is structurally related to propyl gallate and other gallic acid esters that are widely used antioxidants in food and cosmetics. The ortho-dihydroxy (catechol) structure confers antioxidant activity but also introduces sensitisation potential through oxidation to quinone-type reactive intermediates. EU CosIng does not list this specific substance in Annex II or III, but gallate antioxidants are generally scrutinised under preservation efficacy and sensitisation frameworks. The 3,4-dihydroxy substitution pattern is of slightly higher concern than the fully alkyl-substituted gallates, resulting in a moderate-low score.

Skin benefits

  • Antioxidant protection
  • Preservative synergist

Known concerns

  • Minor sensitisation potential from catechol group
  • Oxidation to quinone-reactive intermediates possible

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.