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Banned substance

Cephaeline and its salts

CAS 483-17-0
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Cephaeline is a toxic isoquinoline alkaloid from ipecac and a relative of emetine. It is captured as a prohibited drug substance for cosmetic use, with serious systemic toxicity and no skincare role.

Skin benefits

  • Pharmacologically active emetine relative used historically as an emetic drug
  • Listed only for completeness in cosmetic prohibition lists
  • No cosmetic benefit is recognised

Known concerns

  • Highly toxic alkaloid with cardiotoxic and emetic effects
  • Banned for use in cosmetic products in the EU and many jurisdictions
  • Systemic toxicity even at small doses
  • No safe concentration for skin exposure

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related banned substances

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.