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Skin Conditioning

CHELIDONIUM MAJUS EXTRACT

CAS 84603-56-5 Updated
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Greater celandine extract, traditionally used for warts. Modern data shows real toxicity concerns — EMA documented liver injury from oral use, and skin irritation is common.

Function

ANTI-SEBORRHEIC

Skin benefits

  • Traditional use for blemishes and warts
  • Contains alkaloids with antimicrobial action
  • Astringent toner-like effect

Known concerns

  • Hepatotoxic alkaloids documented in oral use
  • Skin irritation and contact dermatitis reported
  • EMA flagged liver injury risk for internal preparations
  • Inappropriate for sensitive or compromised skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.