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Preservative

CHLORHEXIDINE DIACETATE

CAS 56-95-1 Updated
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A potent cationic antimicrobial used as a preservative — capped by the EU at 0.3% in cosmetics. Highly effective but carries documented sensitisation risk and persistent aquatic toxicity, so use is tightly controlled.

Function

ANTIMICROBIALORAL CAREPRESERVATIVE

Skin benefits

  • Broad-spectrum antimicrobial preservative
  • Effective at very low concentrations
  • Reduces microbial contamination in oral and topical products

Known concerns

  • EU restricts to 0.3% maximum (Annex VI)
  • Skin sensitisation and rare anaphylaxis reports
  • Aquatic toxicity and environmental persistence
  • Tooth/tongue staining in oral applications

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related preservatives

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.