Preservative
DIBROMOHEXAMIDINE ISETHIONATE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A halogenated bisamidine preservative (Annex V/15) capped at 0.1% in EU cosmetics. Effective against gram-positive bacteria and some fungi; cationic structure means it can irritate eyes and sensitise some users.
Function
Skin benefits
- Effective antimicrobial preservative against gram-positives
- Permitted EU preservative under Annex V at 0.1%
- Active in skin and oral hygiene products
Known concerns
- Cationic biocide — can irritate eyes and mucous membranes
- Halogenated structure raises persistence flags
- Sensitisation reports in clinical literature
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related preservatives
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.