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chlormadinone

CAS 1961-77-9
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Chlormadinone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Chlormadinone acetate is a synthetic steroidal progestogen with anti-androgenic properties used in pharmaceutical oral contraceptives. The EU Cosmetics Regulation 1223/2009 Annex II explicitly prohibits this substance for cosmetic purposes due to its steroid hormone activity. CAS 1961-77-9 presents concerns for hormonal disruption when applied topically, and no safe use level has been established for cosmetic formulations.

Known concerns

  • EU Annex II banned — anti-androgenic progestogen
  • Endocrine disruption potential
  • No safe cosmetic use threshold established

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.