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Chlormethine (INN) and its salts

CAS 51-75-2
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Chlormethine (INN) and its salts is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Chlormethine (mechlorethamine) is a potent alkylating agent classified as a CMR substance (Carcinogenic, Mutagenic, toxic for Reproduction Category 1B) under EU Regulation 1272/2008 (CLP). It is listed on EU Annex II of prohibited substances in cosmetics (Regulation EC No 1223/2009) and must never be used in cosmetic products. Its hazard profile includes H350 (carcinogen), H340 (germ cell mutagen), H300/H310 (acute toxicity).

Known concerns

  • CMR substance (Cat 1B)
  • EU Annex II banned
  • severe acute toxicity
  • carcinogen
  • mutagen

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.