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CHRYSANTHEMUM ZAWADSKII FLOWER VESICLES

73

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Innovative chrysanthemum flower vesicle extract for advanced skin delivery

Vesicle-based delivery systems (often liposomal or phytosomal) for Chrysanthemum zawadskii extract are designed to encapsulate the bioactive constituents — including flavonoids, phenolic acids, and sesquiterpene lactones — within a phospholipid or polysaccharide membrane. This formulation approach reduces direct exposure of sensitising compounds to the skin surface, potentially lowering the risk of Asteraceae contact dermatitis compared to unencapsulated extract. EU Regulation 1223/2009 does not distinguish between vesicle-encapsulated and conventional forms for restriction purposes, but the vesicle format may reduce irritancy and is generally considered a safety-improving formulation strategy. The ingredient still carries mild Asteraceae allergen concern in the overall scoring range (60–74).

Skin benefits

  • Controlled-release delivery may enhance antioxidant and anti-inflammatory efficacy over time
  • Encapsulation reduces direct skin irritation compared to free extract
  • Retains all bioactive flavonoids and phenolic compounds

Known concerns

  • Sesquiterpene lactone content remains present; vesicle formulation may reduce but does not eliminate contact-allergen risk
  • Allergen declaration still recommended for EU compliance under Regulation 1223/2009

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.