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CIS-3-HEXENYL 2-METHYLBUTYRATE

CAS 53398-85-9
64

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A fruity-green ester with a character reminiscent of tropical fruits, classified as an environmental hazard (H411) requiring careful handling and disposal but not directly restricted in EU cosmetic formulations.

cis-3-Hexenyl 2-methylbutyrate is an unsaturated ester with a distinctive fruity-green odor profile. It carries GHS hazard statement H411 (toxic to aquatic life with long-lasting effects), which requires environmental risk assessment in cosmetic product life-cycle; however it is not listed in EU CosIng Annex III restrictions. It is not considered a strong sensitizer but must be declared as a fragrance allergen in EU cosmetics above threshold levels under Regulation (EC) No 1223/2009.

Known concerns

  • H411 — toxic to aquatic life with long lasting effects
  • fragrance allergen — EU label declaration required

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.