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Skin Conditioning

CISSAMPELOS PAREIRA BARK EXTRACT

CAS 93333-87-0 Updated
46

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Velvetleaf (Cissampelos pareira) bark extract — an Ayurvedic botanical containing pharmacologically active alkaloids like tetrandrine. Thin dermal safety data plus active drug-like chemistry keep it in cautious orange territory.

Function

SKIN CONDITIONING

Skin benefits

  • Traditional Ayurvedic skin use
  • Tetrandrine alkaloid content
  • Antioxidant

Known concerns

  • Bisbenzylisoquinoline alkaloids are pharmacologically active
  • Limited dermal safety data
  • Hepatic concerns reported orally
  • Default-down for active alkaloid chemistry

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.