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CISSAMPELOS PAREIRA ROOT POWDER

CAS 93333-87-0
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Velvet leaf root powder used in traditional herbal formulations for skin health.

Cissampelos pareira contains alkaloids including berberine, cissamparine, and hayatine. The plant has a history of use in traditional medicine but also contains potentially toxic alkaloids requiring careful safety evaluation. It is not listed in EU cosmetic Annexes, but the presence of curare-like alkaloids warrants caution regarding prolonged topical exposure.

Skin benefits

  • traditional anti-inflammatory use
  • antimicrobial

Known concerns

  • contains potentially toxic isoquinoline alkaloids
  • limited cosmetic-specific safety data
  • contraindicated in pregnancy

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.