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Banned pharmaceutical

clocortolone

CAS 4828-27-7
2

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A halogenated prescription corticosteroid used to treat dermatitis under medical supervision. It is banned from cosmetics in the EU because chronic use thins the skin and disrupts hormonal balance.

Skin benefits

  • No legitimate cosmetic function
  • Prescription topical corticosteroid only

Known concerns

  • EU Cosmetic Regulation Annex II prohibits corticosteroids
  • Causes skin atrophy and HPA-axis suppression on prolonged use
  • Halogenated steroid associated with rebound dermatitis
  • Sometimes found illegally in skin-lightening creams

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related banned pharmaceuticals

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.