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clocortolone

CAS 4828-27-7
20

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Clocortolone is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Clocortolone is a synthetic fluorinated corticosteroid indicated for inflammatory skin conditions such as eczema and psoriasis. It is a prescription-only topical steroid with a potency rating in the medium-to-high range. Long-term or inappropriate use leads to skin thinning, striae formation, and potential systemic corticosteroid absorption. EU cosmetic regulations prohibit the use of registered therapeutic steroids in cosmetic products.

Known concerns

  • Prescription-only topical steroid — not permitted in cosmetics
  • Risk of skin atrophy and striae with prolonged use
  • Systemic corticosteroid absorption possible

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.