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Banned Substance

Colchicum autumnale L. and its galenical preparations

CAS 84696-03-7 Updated
1

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Autumn crocus (Colchicum autumnale), the natural source of colchicine. Listed in EU Annex II as prohibited in cosmetics because of severe systemic toxicity.

Skin benefits

  • No cosmetic benefit; banned under EU Annex II

Known concerns

  • EU Annex II prohibition
  • Colchicine has antimitotic toxicity
  • Reproductive and bone marrow risks

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.