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DEMETHOXYCURCUMIN

CAS 22608-11-3
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A naturally occurring curcuminoid from turmeric rhizome that provides antioxidant and anti-inflammatory benefits for skin.

Demethoxycurcumin is a major curcuminoid analogue found in turmeric (Curcuma longa) rhizome extract. Like curcumin, it demonstrates antioxidant, anti-inflammatory, and antimicrobial properties. In the EU, turmeric extract is permitted as a cosmetic ingredient with no specific restriction; however, curcuminoids may require supplier-specific purity assessment. Cross-sensitivity with other cinnamic acid derivatives is a theoretical concern.

Skin benefits

  • Potent antioxidant activity
  • Anti-inflammatory skin calming
  • Antimicrobial properties
  • May help reduce hyperpigmentation

Known concerns

  • Theoretical cross-reactivity with cinnamate sensitisers
  • Limited data on long-term topical use at high concentrations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.